Our Impact

Veterinarian holds black mouse in laboratory
Thursday, February 22, 2018 Mouse Study Could Pave the Way for New Approaches to Treating Obesity
"Whenever you generate mice exhibiting human disease-like phenotypes,” notes study team lead Ling Qi, Ph.D., “you know you are working on something with fundamental importance."
Zebrafish swims in shuttle tank with enrichment items
Friday, February 9, 2018 Newly Identified RNA Protein in Zebrafish, Mice Could Serve as a Target for the Development of a New Cancer-Fighting Drug
Researchers at the University of Michigan Comprehensive Cancer Center have identified and characterized a new long noncoding RNA (lncRNA), called THOR, that is expressed in humans, mice, and zebrafish. It’s unusual for this type of RNA to be conserved throughout species like this. The team’s thinking was that if the RNA plays a role in other animals and species besides humans, it must be important.
White rat being held by laboratory animal technician
Sunday, February 4, 2018 New Rodent Study Illustrates How Boosting A Key Protein May Help Repair Bone Injuries
A new study, conducted in mice and rats, finds that delivering additional Jagged-1 – a potent osteoinductive protein known to activate the Notch signaling pathway that regulates bone healing – could help jump-start the body’s natural process to repair bone injuries in some patients.
Researcher holding white mouse in tunnel
Monday, January 22, 2018 Who Might Benefit from Immunotherapy? Mouse Study Suggests Possible Marker
Based on study conducted in mice with colon cancer, ovarian cancer, melanoma, and lung cancer, researchers have discovered that PD-L1 in cells within the tumor microenvironment and lymph nodes may matter more than PD-L1 in tumors.
Researcher examines mouse cages
Sunday, January 7, 2018 Mouse Models Help Researchers Explore Pancreatic Cancer Treatment
Researchers from Michigan Medicine and the University of California San Francisco are using mouse models to explore the important role that the protein PDX1 plays in the development and treatment of pancreatic cancer.
Guinea pigs eating hay
Thursday, January 4, 2018 Guinea Pigs Play a Crucial Role in the Development of a New Treatment Device to Ease Tinnitus Symptoms
After years of research into the root causes of tinnitus, a team of University of Michigan researchers has developed a new experimental treatment device that uses specially timed auditory and electrical signals, first discovered in guinea pigs, to ease tinnitus symptoms.
Two black mice play in clear tunnel with nesting material
Monday, November 27, 2017 Mouse Model Demonstrates How Synthetic Hydrogels Stimulate Real-Life Intestinal Healing
The early successes of engineered polymeric materials known as hydrogels in animal models represent a new way to heal intestinal damage — a process that one day might be applied to other injured organs.
Laboratory personnel holds small brown mouse
Friday, November 10, 2017 Animal Model Offers New Hope for Tackling Triple-Negative Breast Cancer
Using an animal model, U-M researchers have found that a novel drug combination disrupts multiple factors in an aggressive type of breast cancer.
Female researcher looks into microscope in laboratory
Friday, October 27, 2017 Examining Sepsis: Could a Large Animal Model Unravel the Disease?
New research using a large animal model hopes to uncover new diagnostic and resuscitative strategies for this difficult-to-treat condition.
Brown laboratory mouse in nesting material
Wednesday, October 11, 2017 From Urine Output to Disease, Mouse Study Shows Importance of Hormone Quality Control
Discovering a puddle of mouse urine seems like a strange scientific “eureka” moment. But for one research team, it’s exactly what led to a new discovery.

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