IVAC, MMPC Offer Specialized Services and Support for Metabolic Disease and Diabetes-Related Mouse Models
The In-Vivo Animal Core (IVAC) and Gnotobiotic Facility, part of the Unit for Laboratory Animal Medicine (ULAM), are participants in the Mouse Metabolic Phenotyping Center (MMPC) at the University of Michigan.
Funded by NIH Grant Number U2CDK110768, the Michigan MMPC
is one of six centers in a larger NIH-funded national consortium offering standardized, high-quality metabolic and physiologic phenotyping services.
U-M investigators requesting research services that relate to mouse models of diabetes, diabetic complications, obesity, and related metabolic diseases and conditions may be eligible for supplemental support for qualified tests and services provided through IVAC and Gnotobiotic Facilities.
To discuss the specific needs of your research project, or for more information about MMPC services, please contact:
Animal Care & Germ-Free Mouse Core (visit website)
| Focus | Director | Phone Number | |
|---|---|---|---|
| Gateway for all phenotyping involving live mice; providing mouse importation, quarantine, housing, veterinary care, clinical chemistry and histopathology services. |
Robert Sigler, DVM, PhD, DACVP Robert C. Dysko, DVM, DACLAM Kathryn A. Eaton, PhD, DVM, DACVP |
ulam-ivac@umich.edu |
(734) 647-0731 |
Metabolism, Bariatric Surgery & Behavior Core (visit website)
| Focus | Director | Phone Number | |
|---|---|---|---|
| Performs a variety of in-vivo physiological assessments encompassing glucose homeostasis, energy homeostasis, ultradian hormone secretion and behavioral measurements, and generation of bariatric surgery models. |
mlschmi@med.umich.edu |
(734) 764-7043 |
Microvascular Complications Core (visit website)
| Focus | Director | Phone Number | |
|---|---|---|---|
| Provides a complete range of microvascular phenotpying of murine models of diabetes, obesity and metabolic disease; including validated, reproducible, and standardized phenotyping of the three major microvascular complications: diabetic polyneuropathy, nephropathy, and retinopathy. |
chengmao@med.umich.edu |
(734) 232-8220 |
Microbiome Core (visit website)
| Focus | Director | Phone Number | |
|---|---|---|---|
|
Analyzes microbiome structure |
midority@umich.edu |
(734) 764-3016 |
Additional information about each MMPC core, including how to submit a request for services, is available on the MMPC website. Information about ULAM’s In-Vivo Animal Core, including a full list of available services, sample submission forms, and sample drop-off details, is available on the IVAC webpage.