Reminder: Three-Page DEA Form 222 to Be Replaced in October

September 8, 2021

New Single-Page DEA Form 222 Reminder iconBeginning October 30, 2021, all DEA registrants will be required to use the new single-page DEA Form 222 to purchase, transfer, or dispose of Schedule I and Schedule II controlled substances.

The old Form 222, a carbon-copy triplicate form, will no longer be accepted after October 30. Any extra unused copies of the discontinued three-page form must be sent back to the DEA for proper destruction.

Copies should be sent to:

Drug Enforcement Administration
431 Howard Street
Detroit, MI 48226


All U-M DEA registrants and their associated staff will receive a final email reminder to order new single-page Form 222s via the DEA website and to send all forms back to the DEA prior to the October 30 implementation date.

Instructions for filling out the new single-page form are available here (via PDF download). Please refer to this document when placing your Schedule I or II orders as directions have changed.


Questions or concerns should be directed to the U-M Office of Research (UMOR) Controlled Substances Monitoring Program at