Our Impact

red cell image with green lines
Thursday, May 4, 2023 A Gene Involved in Down Syndrome Puts the Brakes on Neurons’ Activity in Mice, Study Shows
Researchers find an extra copy of one gene is triplicated in human Down syndrome patients, causing improper development of neurons in mice.
Small black mouse walks on reflective surface under laboratory safety hood
Monday, April 17, 2023 Mouse Study Hints at Specific Brain Receptor Behind PCOS Symptoms
Basic research is getting closer to potential therapeutic targets.
cells in pink and teal
Friday, March 24, 2023 Using the Power of Artificial Intelligence
New open-source tool simplifies animal behavior analysis.
cell slides under microscope
Wednesday, February 15, 2023 P53 Could Be Key to Therapies for Salivary Gland Cancer
Mouse models show that activating a non-mutated form of the gene could lead to developing therapies for this deadly form of cancer.
Microscopic mouse model of human colorectal cancer
Monday, January 9, 2023 High Levels of Ammonia in Colon Tumors Inhibit T Cell Growth and Response to Immunotherapy
In mouse models and serum samples, an FDA-approved drug that lowers ammonia levels made the tumors more sensitive to treatment.
suPAR cells blood vessels plaque
Thursday, December 15, 2022 New Immune Target to Treat Cardiovascular Disease Discovered
The protein, suPAR, has been found to cause atherosclerosis and kidney disease, raising potential for new treatments.
Green staining shows mTORC1 is significantly increased due to disruption in GATOR1 in a mouse model of colon cancer. Credit: Sumeet Solanki, Ph.D.
Monday, November 21, 2022 Dietary Change Starves Cancer Cells, Overcoming Treatment Resistance
Laboratory research finds a low-protein diet can enhance standard treatment for colon cancer.
Blue and white Illustration of brain with highlighted area of red
Tuesday, October 4, 2022 New Clues Toward Treating Pediatric Brain Tumors Harboring Epigenetic Mutation
Inhibition of STAT3 signaling may improve survival in those with H3.3G34R/V mutant gliomas, animal studies suggest.
Elderly couple sit side by side laughing while man whispers into woman's ear
Tuesday, September 27, 2022 How a Single Protein Can Slow Down Age-Related Hearing Loss
Study in mice suggests that the overexpression of cochlear neurotrophin-3 can help prevent the loss of hearing.
Image of a mouse tumor stained to show specific markers. Provided provided by Monique Verhaegen
Wednesday, September 21, 2022 Viral Proteins Key to Tumor Model in Mice
Researchers have figured out how to create a mouse model of a rare but fatal skin cancer, a scientific discovery 10 years in the making.

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