Associate Attending Veterinarian for Performance Standards and Enrichment
Jennifer Lofgren, DVM, MS, DACLAM is a Clinical Assistant Professor with the Unit for Laboratory Animal Medicine, where she provides clinical veterinary support, protocol review, mentorship, and lecture support to residents. Dr. Lofgren also serves as the Associate Attending Veterinarian of Practice Standards and Enrichment and as the Faculty Advisor for the Enrichment and Social Housing Committee, where she helps animal use protocols meet or exceed laboratory animal science standards and regulations to achieve scientifically sound animal welfare excellence.
In partnership with fellow U-M faculty veterinarian Dr. Jean Nemzek, Dr. Lofgren founded the Refinement & Enrichment Advancements Laboratory (REAL) at the U-M in 2014. As one of the country’s only laboratories dedicated to optimizing biomedical research efforts through improved animal well-being, REAL seeks to understand the relationship between the animal’s lived experience and scientific results. As part of this work, Dr. Lofgren has received three grants, including both the American College Laboratory Animal Medicine (ACLAM Foundation) and the American Association for Laboratory Animal Science (GLAS), to support nociceptive and behavioral research to identify pain behaviors and effective alleviation of pain in rodent species.
Prior to joining the University of Michigan, Dr. Lofgren completed a visiting research fellowship at Newcastle University, where she learned how to conduct scientifically rigorous studies that isolate and evaluate pain behavior in rodents. She became a Diplomate of the American College of Laboratory Animal Medicine in 2011 after completing post-doctoral training in Comparative Medicine at the Massachusetts Institute of Technology (MIT). While at MIT, Dr. Lofgren engaged in infectious disease and cancer research, as well as refining husbandry and veterinary care to improve animal welfare. Dr. Lofgren completed a dual degree Masters in Comparative Biomedical Sciences and a Doctorate of Veterinary Medicine from Tufts University.
Dr. Lofgren's professional interests include minimizing pain and distress in laboratory animals as a clinical veterinarian, educator, and research scientist. She also enjoys engaging in teaching, training and mentoring, and conducting and collaborating on research.
- BA, Wellesley College
- DVM, Tufts University, Cummings School of Veterinary Medicine
- MS, (Comparative Biomedical Sciences), Tufts University
- Diplomate, American College of Laboratory Animal Medicine (ACLAM)
- Lofgren JLS, Esmail M, Mobley M, McCabe A, Taylor NS, Shen Z, Erdman S, Hewes C, Whary MT, Fox JG. Prevalence of murine Helicobacter spp. infection is reduced by restocking research colonies with helicobacter-free mice. Journal of the American Association of Laboratory Animal Science. 51(4):436-42, 2012.
- Lofgren JLS, Erdman SE, Hewes C, Wong C, King R, Chavarria TE, Discua AR, Fox J G, Maurer KJ. Castration eliminates conspecific aggression in group housed CD-1 male surveillance mice (Mus musculus). Journal of the American Association of Laboratory Animal Science. 51(4): 436-442, 2012.
- Lofgren JLS, Whary MT, Ge Z, Muthupalani S, Taylor NS, Mobley M, Potter A, Varro A, Wang TC, Fox JG. Helicobacter pylori monoassociated INS-GAS mice develop attenuated gastritis and delayed gastrointestinal intraepithelial neoplasia. Gastroenterology. 140(1), 210-220, 2011.
- Rozanski EA, Bedenice D, Lofgren JLS, Abrams J, Bach J, Hoffman AM. The effect of body position, sedation, and thoracic bandaging on functional residual capacity in healthy deep-chested dogs. Can J Vet Res. 74(1):34-9, 2010.
- Lofgren JLS. Gap Between D & E (Response to “Categorizing insufficient pain alleviation.”) Lab Animal. 38(11), 345-347, 2009.
- Jackson CN, Rogers AB, Maurer KJ, Lofgren JLS, Fox JG, Marini RP. Cystic renal disease in the domestic ferret. Comparative Medicine. 58(2), 161-167, 2008.
- Bach JF, Rozanski EA, Bedenice D, Chan DL, Freeman LM, Lofgren JLS, Oura TJ, Hoffman AM. Association of expiratory airway dysfunction with marked obesity in healthy adult dogs. Am J Vet Res. 68(6), 670-675, 2007.
- Lofgren JLS, Mazan MR, Ingenito EP, Lascola K, Seavy M, Walsh A, Hoffman AM. Restrained whole body plethysmography for measure of strain-specific and allergen-induced airway responsiveness in conscious mice. J Appl Physiol., 101, 1495-1505, 2006.
- Bedenice D, Rozanski E, Bach J, Lofgren JLS, Hoffman AM. Canine awake head-out plethysmography (HOP): characterization of external resistive loading and spontaneous laryngeal paralysis. Respir Physiol Neurobiol., 151(1), 61-73, 2006.