Zachary T. Freeman, DVM, PhD, DACLAM

Profile

Zachary Freeman is a veterinary scientist focused on improving genetically modified animal models to increase translational reproducibility and relevance to human disease. He has developed multiple approaches to leverage advanced sequencing methods to assess intended and unintended genomic changes associated with genetically modified laboratory animals. He currently serves as the Director of the University of Michigan Transgenic Animal Model Core, which generates CRISPR/Cas9-engineered mouse and rat models for biomedical researchers from across the world.

In his clinical capacity, Dr. Freeman serves as the Program Director for the Rodent Health Surveillance Program, which is responsible for the management of infectious agents in multiple laboratory animal species, including mice, rats, rabbits, fish, xenopus, and various USDA-covered rodent strains. Freeman is also co-Director of the National Center of Rabbit Models for Translational Research.

He has significant expertise in the management of infectious diseases in highly immunodeficient animal models and has developed specific strategies to improve the use of these models in research.

RESEARCH INTERESTS

Dr. Freeman’s research interests include improving the characterization and use of genetically modified animals to increase reproducibility and translational relevance.