Report Animal Concerns

Our Mission

The Animal Care & Use Program supports the University of Michigan community in its pursuit of impactful science to benefit both human and animal health by fostering a culture of excellence and compassion, responsible research conduct, and a shared commitment to upholding the highest animal welfare standards in all aspects of research and instruction.

A Message from Our Leadership

For decades, laboratory animals have been essential to almost every major advancement in human and animal medicine. The University of Michigan (U-M) community is committed to the highest standards of excellent and humane care in the use of these animals in our research and instruction, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as “the three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support the entire U-M community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 

William King, DVM, PhD, DACLAM
Associate Vice President for Research – Animal Care and Use Program
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research – Animal Program Compliance Oversight
Director, Animal Care & Use Office

Daniel D. Myers, DVM, MPH, DACLAM
Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Our Impact

Technician holds white rat

Studies Uncover the Critical Role of Sleep in the Formation of Memories

Sleep—or a lack thereof—has a dramatic effect on neurons in the hippocampus. Imagine you’re a student, it’s finals week, and you’re preparing for a big exam: do you pull an all-nighter or do you get some rest?  As many a groggy-eyed person who’s stared blankly at a test knows, a lack of sleep can make …
Graphic of a person’s body with a missing puzzle piece of red heart being placed into top left shoulder chest location where piece is missing

Normothermic Perfusion System Extends Life of Organs Waiting for Transplant

The system could increase the number of hearts considered for transplant. In the United States, about 30-40% of donor hearts aren’t considered for transplant due to inadequate function in the donor.  This creates a drop in the number of donated hearts that are available to be matched with someone who needs a heart transplant. A …
Illustration of human heart anatomy

Researchers Create Human Aortic Aneurysm Model to Advance Disease Understanding, Treatment Testing

When implanted into laboratory rats, the model successfully mimicked dilation of the human aorta. Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests. There are currently no …


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