Our Mission

The Animal Care & Use Program fosters a culture of excellence, compassion, and adherence to the highest standards of animal welfare in the conduct of research, testing, and teaching at the University of Michigan.

A Message from Our Leadership

Male and female scientist in laboratory performing biopsy

For decades, laboratory animals have been essential to almost every major advance in human and animal medicine. The University of Michigan community is committed to the highest standards of excellent and humane care in the use of these animals in its research, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as “the three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support our campus-wide research community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 

Regards,

S. Jack Hu, PhD
Vice President for Research
Professor of Engineering
Institutional Official

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research - Animal Program Compliance Oversight
Director, Animal Care & Use Office

William King, DVM, PhD, DACLAM
Assistant Vice President for Research - Animal Resources
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

Daniel D. Myers, DVM, MPH, DACLAM
Associate Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Close up image of a cancer cell
Tuesday, September 18, 2018Mouse Study Provides Potential Breakthrough in Defeating Cancer Stem Cells
Thanks to a new mouse study, U-M researchers have discovered why stem cells become resistant to cancer treatment and are now developing therapies to combat this resistance.
Researcher donning PPE examines mouse under flow hood
Monday, September 17, 2018Researchers Look to Mouse Models to Gain Better Understanding of Heart Abnormalities in Patients with Dravet Syndrome
U-M researchers first looked at mouse models, and then at cells collected from children with Dravet syndrome, to identify a gene mutation that may lead to irregularities in the heart muscle’s sodium channels; irregularities that could trigger sudden unexpected death in epilepsy (SUDEP). With this important foundation in place, the research team now plans to look at different gene mutations related to SUDEP, and at the potential use of re-purposed drugs to treat Dravet syndrome and other forms of epilepsy.
Researcher donning green gloves holds small black mouse
Monday, July 30, 2018Mice Help Researchers Uncover Intricate Cellular Process Critical to Small Intestine Development
More than 40 percent of our small intestine develops before we are even born. But problems with this process in utero can result in a rare but deadly condition known as congenital short bowel syndrome. A new Michigan Medicine study conducted with mice has helped researchers uncover the surprising sequence of cellular events responsible for proper development of the small intestine.

Questions?

As a public institution and an accredited site for animal use, we are open to inquiries, reports of concern, or other communications from within and beyond the U-M. Questions about the care and use of laboratory animals at the University of Michigan should be directed to acuoffice@umich.edu