Report Animal Concerns

Our Mission

The Animal Care & Use Program supports the University of Michigan community in its pursuit of impactful science to benefit both human and animal health by fostering a culture of excellence and compassion, responsible research conduct, and a shared commitment to upholding the highest animal welfare standards in all aspects of research and instruction.

A Message from Our Leadership

For decades, laboratory animals have been essential to almost every major advancement in human and animal medicine. The University of Michigan (U-M) community is committed to the highest standards of excellent and humane care in the use of these animals in our research and instruction, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as β€œthe three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support the entire U-M community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 

Regards,
 
William King, DVM, PhD, DACLAM
Associate Vice President for Research – Animal Care and Use Program
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research – Animal Program Compliance Oversight
Director, Animal Care & Use Office

Daniel D. Myers, DVM, MPH, DACLAM
Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Our Impact

Stock image of common food allergens and ingredients

Nanoparticles Reprogram Mouse Immune Systems to Cope with Allergens

Treatment suppressed anaphylaxis and reduced gut inflammation after just two intravenous infusions. Two doses of allergen-encapsulating nanoparticles delivered intravenously prevented anaphylaxis during a food allergy test in mice, according to a study led by University of Michigan researchers.  The results, published in Advanced Healthcare Materials, offer a potential path to improving the ease of allergy immunotherapies in …
Illustration showing sewing machine cell fabric tangled

Research Points to Potential New Treatment for Aggressive Prostate Cancer Subtype

In two separate papers, U-M researchers describe how a gene alteration drives prostate cancer and a potential degrader that stops it. When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to …
Activation of tachykinin 1-expressing neurons in the nucleus of the solitary tract (highlighted in white) triggers cough-like behavior in mice, according to new research from the LSI.

Researchers Have Determined How Mice Cough, and It Matters for Humans

A team of scientists from the University of Michigan have now mapped the circuit that controls one often-irritating form of exhaling, the cough, using a model organism that was not previously known to exhibit this behavior. Yawns, sighs, regular breath β€” all these seemingly automated forms of inhaling and exhaling are coordinated by unique neuronal …

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