Re-Evaluating Mouse Cage Changing Techniques: Use of Forceps vs. Gloved Hands

ULAM’s standard cage changing practices have required Animal Technicians to use forceps when transferring mice between cages for the past two decades. However, research^1,2,3,4 has shown that handling of animals with forceps is associated with a higher incidence of repetitive motion injuries in animal care and use personnel.

In an effort to help mitigate this ergonomic risk while still ensuring that overall animal health and safety are maintained at all times, ULAM re-evaluated our mouse cage changing techniques and reviewed the practices of peer institutions.

Our survey revealed that a majority of our peers offer an alternative to the use of forceps for transferring mice in between cages, and that the most commonly cited alternate method⁵ is the use of disinfected-gloved hands.

An internal study conducted within ULAM did not suggest that the use of gloved hands poses a cross-contamination risk to animals. There were no adverse effects on overall colony health and breeding performance identified during our study period. Additionally, husbandry guidelines for microisolator technique and changing gloves between investigators and rack sides will continue to be observed as measures to prevent contact between groups of animals.

** Note: Forceps will continue to be available in all rooms for mouse handling.
These changes do NOT apply to cage changing in biocontainment rooms, which will continue to be forceps-only. **

For more information on alternative handling methods, or for details regarding our institutional study, please contact your ULAM Faculty Veterinarian. If you don’t know your faculty veterinarian, send an email to ulam-questions@umich.edu and your question will be routed appropriately.