Our Mission

The Animal Care & Use Program fosters a culture of excellence, compassion, and adherence to the highest standards of animal welfare in the conduct of research, testing, and teaching at the University of Michigan.

A Message from Our Leadership

Male and female scientist in laboratory performing biopsy

For decades, laboratory animals have been essential to almost every major advance in human and animal medicine. The University of Michigan community is committed to the highest standards of excellent and humane care in the use of these animals in its research, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as “the three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support our campus-wide research community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 

Regards,

Rebecca Cunningham, MD
Institutional Official
Vice President for Research
William G. Barsan Collegiate Professor of Emergency Medicine

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research – Animal Program Compliance Oversight
Director, Animal Care & Use Office

William King, DVM, PhD, DACLAM
Assistant Vice President for Research – Animal Resources
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

Daniel D. Myers, DVM, MPH, DACLAM
Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Technician holds brown mouse
Monday, August 16, 2021Mouse Study Suggests that Targeting Skin Protein May Limit Inflammation in Psoriasis Patients
Using a model that mimics psoriasis in mice, researchers found that changing the levels of interferon kappa, a protein made by skin cells, altered the severity of inflammation and production of cell signaling molecules, called cytokines, that induce inflammation characteristic of psoriasis.
Foreground (from left): Research Laboratory Technician Anne Marie Weitzel, PC3L Associate Director Brendan McCracken, MS, and PC3L Director Hakam Tiba, MD, MS. Background: Research Laboratory Technician Carmen Colmenero, BS.
Monday, August 2, 2021New Preclinical Research Models Could Lead to Better Diagnosis, Treatment of Sepsis and ARDS
Novel large animal research models developed at the University of Michigan Center for Integrative Research in Critical Care fill a crucial gap in the translational study of life-threatening critical illness and injury.
This sample of clinical triple-negative breast cancer is stained for bone morphogenetic protein-11 (red); the Golgi marker GM130 (green); glycosylated proteins (white); and nuclei (blue), illustrating profound molecular heterogeneity.
Wednesday, July 28, 2021Mouse Models Aid in the Search for New Approaches to Treat Triple-Negative Breast Cancer
Breast cancer stem cells from patients with different racial and ethnic backgrounds showed important differences in activation of immune response-related genes in mouse models. This work suggests that further exploration may help develop new approaches to treat triple-negative breast cancer, thus helping reduce survival disparities in women with African ancestry.

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Questions?

As a public institution and an accredited site for animal use, we are open to inquiries, reports of concern, or other communications from within and beyond the U-M. Questions about the care and use of laboratory animals at the University of Michigan should be directed to the Animal Care & Use Office at acuoffice@umich.edu.

If you are a member of the media, or have a media inquiry, please email acu-media@umich.edu or call the Michigan Medicine Department of Communication at (734) 764-2220 and your question will be routed to the appropriate media team member.