Our Mission

The Animal Care & Use Program fosters a culture of excellence, compassion, and adherence to the highest standards of animal welfare in the conduct of research, testing, and teaching at the University of Michigan.

A Message from Our Leadership

Male and female scientist in laboratory performing biopsy

For decades, laboratory animals have been essential to almost every major advance in human and animal medicine. The University of Michigan community is committed to the highest standards of excellent and humane care in the use of these animals in its research, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as “the three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support our campus-wide research community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 


Rebecca Cunningham, MD
Institutional Official
Interim Vice President for Research
Director, U-M Injury Prevention Center
Professor, Emergency Medicine

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research - Animal Program Compliance Oversight
Director, Animal Care & Use Office

William King, DVM, PhD, DACLAM
Assistant Vice President for Research - Animal Resources
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

Daniel D. Myers, DVM, MPH, DACLAM
Associate Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Husbandry technician holds white mouse in germ-free facility
Friday, December 13, 2019Germ-Free Mice May Hold New Clues for Better Treatment of Iron-Related Disorders
In a study involving germ-free mice, Michigan Medicine researchers have unlocked a mechanism behind how the body decides whether or not to absorb iron from the food–one that involves the trillions of bacteria in our guts known as the gut microbiome. What these intriguing findings suggest is an unconventional treatment for iron-related disorders, such as anemia.
A potent and selective degrader of the transcription factor STAT3 offers a new approach to a previously “undruggable” target.
Friday, November 15, 2019U-M Compound Achieves Lasting Tumor Regression of Leukemia and Lymphoma in Mouse Models
A potent and selective degrader of the transcription factor STAT3 offers a new approach to a previously “undruggable” target. In a mouse model of leukemia, the degrader eliminated all of the tumors, with the mice remaining tumor-free for 60 days. In two mouse models of lymphoma, the drug eliminated all of the tumors for more than 100 days.
White mouse climbs over bedding into clear enrichment tunnel
Friday, November 1, 2019Discovery in Mice Could Remove Roadblock to More Insulin Production
New research published in Nature Immunology shows that a combination of two immune-system factors could open up new avenues for treating Type 1 and Type 2 diabetes and obesity.


As a public institution and an accredited site for animal use, we are open to inquiries, reports of concern, or other communications from within and beyond the U-M. Questions about the care and use of laboratory animals at the University of Michigan should be directed to the Animal Care & Use Office at acuoffice@umich.edu.

If you are a member of the media, or have a media inquiry, please email acu-media@umich.edu or call the Michigan Medicine Department of Communication at (734) 764-2220 and your question will be routed to the appropriate media team member.