Our Mission

The Animal Care & Use Program fosters a culture of excellence, compassion, and adherence to the highest standards of animal welfare in the conduct of research, testing, and teaching at the University of Michigan.

A Message from Our Leadership

Male and female scientist in laboratory performing biopsy

For decades, laboratory animals have been essential to almost every major advance in human and animal medicine. The University of Michigan community is committed to the highest standards of excellent and humane care in the use of these animals in its research, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as “the three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support our campus-wide research community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 

Regards,

Rebecca Cunningham, MD
Institutional Official
Vice President for Research
William G. Barsan Collegiate Professor of Emergency Medicine

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research - Animal Program Compliance Oversight
Director, Animal Care & Use Office

William King, DVM, PhD, DACLAM
Assistant Vice President for Research - Animal Resources
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

Daniel D. Myers, DVM, MPH, DACLAM
Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Brown mouse in laboratory
Wednesday, October 14, 2020Making a New Mouse Could Transform COVID-19 Research
U-M researchers have figured out how to solve a big problem in COVID-19 research: mice, unlike humans, are not susceptible to the disease. Phil King, Ph.D., professor of microbiology and immunology, with the help of researchers in his lab and the U-M Transgenic Animal Model Core, is genetically engineering a new mouse that will allow scientists to study the effects of COVID-19 on various cell types. Once researchers know where the disease does most of its dirty work, they can begin to create targeted therapies.
Two U-M researchers look at slide in lab studying glioblastoma
Tuesday, September 29, 2020Study Suggests New Approach to Improve Radiation Therapy Resistance in Glioblastoma
Laboratory research involving mouse models paves the way for a clinical trial to see if an FDA-approved drug used to prevent organ transplant rejection can work against these aggressive brain tumors.
X-ray image of human lungs
Monday, August 17, 2020Oxygen Therapy Harms Lung Microbiome in Mice
To better understand the relationship between oxygen and lung bacteria, researchers designed a series of experiments in mice. When comparing two groups of genetically identical mice—one with bacteria and one without—the mice without bacteria were protected from oxygen-induced lung injury. Ultimately, the study could have implications for the treatment of reduced oxygen levels in critically ill patients.

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Questions?

As a public institution and an accredited site for animal use, we are open to inquiries, reports of concern, or other communications from within and beyond the U-M. Questions about the care and use of laboratory animals at the University of Michigan should be directed to the Animal Care & Use Office at acuoffice@umich.edu.

If you are a member of the media, or have a media inquiry, please email acu-media@umich.edu or call the Michigan Medicine Department of Communication at (734) 764-2220 and your question will be routed to the appropriate media team member.