Report Animal Concerns

Our Mission

The Animal Care & Use Program supports the University of Michigan community in its pursuit of impactful science to benefit both human and animal health by fostering a culture of excellence and compassion, responsible research conduct, and a shared commitment to upholding the highest animal welfare standards in all aspects of research and instruction.

A Message from Our Leadership

For decades, laboratory animals have been essential to almost every major advancement in human and animal medicine. The University of Michigan (U-M) community is committed to the highest standards of excellent and humane care in the use of these animals in our research and instruction, and we believe that this commitment is central to the rigor and impact of our work.

Our approach goes beyond strict adherence to all required guidelines. In addition, we embrace the principles known as “the three Rs”: reducing the number of animals used to the minimum required for the study, replacing animals with less sentient or non-animal models whenever possible, and refining all practices to provide the best animal welfare possible.

Our Program comprises three units that support the entire U-M community and ensure our collective commitment to the welfare of all animals under our care:

Through projects and training activities that span a wide variety of fields, including medicine, dentistry, natural resources and the environment, engineering, public health, and kinesiology, scientific and medical knowledge developed through animal research has saved countless lives and improved health outcomes for both humans and animals.

Some examples of life-changing research projects and teaching programs at the University of Michigan are highlighted in the stories below. 

Regards,
 
William King, DVM, PhD, DACLAM
Associate Vice President for Research – Animal Care and Use Program
Attending Veterinarian
Executive Director, Unit for Laboratory Animal Medicine
Clinical Professor of Laboratory Animal Medicine

William Greer, BS, CPIA, LAT, CM
Assistant Vice President for Research – Animal Program Compliance Oversight
Director, Animal Care & Use Office

Daniel D. Myers, DVM, MPH, DACLAM
Professor of Surgery
Chair, Institutional Animal Care & Use Committee

Our Impact

Black mice in enclosure with nesting and enrichment material

A Treatment-Resistant, Severe Type of Asthma Successfully Modeled in Mice

The model illuminates underlying biology and immune activity of lung cells involved in neutrophilic asthma. A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for asthma, including biologic therapies. This is especially true for a subtype known as eosinophilic asthma—asthma that’s related to the recruitment …
Illustration of microscopic orange cell in blue cells

Mitochondria May Hold the Key to Curing Diabetes

In a study published in Science, researchers at the University of Michigan used mice to show that dysfunctional mitochondria trigger a response that affects the maturation and function of β-cells. Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, are associated with the development of diseases such as …
The magnetoelastic sensor encapsulated in the 3D printed polymer structure. The inset shows the standalone sensor on a penny for scale. Image credit: Nambisan et al., 2024

Stent Sensor Can Warn of Blockages in the Bile Duct

New battery-less and wireless sensor tested in pigs. Stents to treat various blockages in the human body can themselves become blocked, but a new sensor developed at the University of Michigan for stents that are used in the bile duct may one day help doctors detect and treat stent blockages early, helping keep patients healthier. …

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