Protocol Approval

White rats in housing enclosureIn order to ensure that the highest animal welfare standards are maintained along with the conduct of accurate, valid scientific research at the University of Michigan, Principal Investigators and course directors MUST obtain approval from the Institutional Animal Care & Use Committee (IACUC) before initiating any research, testing, or instructional project(s) involving the use of animals.

For more information on projects that may be excused from IACUC review, please visit our Excused Projects page. Visit the Protocol Review page for information on how the IACUC reviews protocols and for details on additional documentation that may be required prior to submission for projects with special circumstances.

Withholding Approval

The IACUC may withhold approval of an activity/protocol under the following conditions:

  • Review of the matter at a convened meeting of a quorum of the IACUC, and
  • With consent of a majority of the quorum present.

If the IACUC decides to withhold approval of an activity/protocol, it will:

  • Provide a written notification with a statement of the reasons for its decisions, and
  • Give the Principal Investigator (PI) an opportunity to respond in person or in writing.

Please note that the IACUC may reconsider its decision based on additional information provided by the PI.

Related Animal Care A-Z Documents


If you have additional questions, or unsure about whether or not your project requires IACUC approval, please contact the Animal Care & Use Office at (734) 763-8028 or