Our Impact

Illustration of mouse looking at peanut
Sunday, April 15, 2018 U-M Researchers Have Developed A New Vaccine That Suppresses Peanut Allergies in Mice
After nearly two decades spent developing a vaccine agent, U-M researchers have translated this work to the development of a vaccine to treat food allergies. In their new study, the team demonstrates that this vaccine may successfully turn off peanut allergy in mice by altering the immune cell response to peanut exposure.
Dr. Robert Bartlett with a patient and family
Tuesday, April 10, 2018 Animal Model, ECMO Technology Used to Help Develop Innovative Artificial Placenta
Using an animal model, U-M researchers are making progress on an extraordinary new artificial womb technology that could one day revolutionize the care of premature infants.
Anteroposterior (AP) x-ray shows signs of non-encapsulated pulmonary cryptococcosis in a human patient infected with Cryptococcus sp. fungal organisms.
Thursday, March 15, 2018 Mouse Model Helps Researchers Examine Specific Mechanisms Underlying Cryptococcal Disease
The results obtained from this animal study may provide important guidance for the development and use of anti-inflammatory therapies to minimize central nervous system injury in patients with severe cryptococcal infections, a major source of illness in people with HIV and AIDS.
Veterinarian holds black mouse in laboratory
Thursday, February 22, 2018 Mouse Study Could Pave the Way for New Approaches to Treating Obesity
"Whenever you generate mice exhibiting human disease-like phenotypes,” notes study team lead Ling Qi, Ph.D., “you know you are working on something with fundamental importance."
Zebrafish swims in shuttle tank with enrichment items
Friday, February 9, 2018 Newly Identified RNA Protein in Zebrafish, Mice Could Serve as a Target for the Development of a New Cancer-Fighting Drug
Researchers at the University of Michigan Comprehensive Cancer Center have identified and characterized a new long noncoding RNA (lncRNA), called THOR, that is expressed in humans, mice, and zebrafish. It’s unusual for this type of RNA to be conserved throughout species like this. The team’s thinking was that if the RNA plays a role in other animals and species besides humans, it must be important.
White rat being held by laboratory animal technician
Sunday, February 4, 2018 New Rodent Study Illustrates How Boosting A Key Protein May Help Repair Bone Injuries
A new study, conducted in mice and rats, finds that delivering additional Jagged-1 – a potent osteoinductive protein known to activate the Notch signaling pathway that regulates bone healing – could help jump-start the body’s natural process to repair bone injuries in some patients.
Researcher holding white mouse in tunnel
Monday, January 22, 2018 Who Might Benefit from Immunotherapy? Mouse Study Suggests Possible Marker
Based on study conducted in mice with colon cancer, ovarian cancer, melanoma, and lung cancer, researchers have discovered that PD-L1 in cells within the tumor microenvironment and lymph nodes may matter more than PD-L1 in tumors.
Researcher examines mouse cages
Sunday, January 7, 2018 Mouse Models Help Researchers Explore Pancreatic Cancer Treatment
Researchers from Michigan Medicine and the University of California San Francisco are using mouse models to explore the important role that the protein PDX1 plays in the development and treatment of pancreatic cancer.
Guinea pigs eating hay
Thursday, January 4, 2018 Guinea Pigs Play a Crucial Role in the Development of a New Treatment Device to Ease Tinnitus Symptoms
After years of research into the root causes of tinnitus, a team of University of Michigan researchers has developed a new experimental treatment device that uses specially timed auditory and electrical signals, first discovered in guinea pigs, to ease tinnitus symptoms.
Two black mice play in clear tunnel with nesting material
Monday, November 27, 2017 Mouse Model Demonstrates How Synthetic Hydrogels Stimulate Real-Life Intestinal Healing
The early successes of engineered polymeric materials known as hydrogels in animal models represent a new way to heal intestinal damage — a process that one day might be applied to other injured organs.